What Is Postpartum Depression (PPD)?

Pregnancy and giving birth are intensely emotional experiences. And while these life-changing events can bring joy, they can also present challenges that make you feel sad, tired, anxious, or depressed.
While postpartum depression can be debilitating, with time and treatment most women can recover and bond with their baby.
Signs and Symptoms of Postpartum Depression
- Depressed mood or intense mood swings
- Decreased interest or pleasure in activities you normally enjoy
- Intense anxiety and panic attacks
- Severe irritability or anger
- Social withdrawal
- Fear of being a bad mother
- Sleep problems, such as insomnia or excessive sleep
- Appetite changes (hardly eating or eating much more than usual)
- Intense irritability or anger
- Difficulty bonding with the baby
- Overwhelming loss of energy or fatigue
- Restlessness
- Decreased ability to concentrate, think clearly, or make decisions
- Sense of guilt, shame, worthlessness, or inadequacy
- Hopelessness
- Excessive crying
- Thoughts of harming yourself or the baby
- Intrusive thoughts that harm could come to the baby
- Repeated thoughts of suicide or death
“If symptoms go beyond a two-week period and the mother is still experiencing problems, that will usually lead to a diagnosis of postpartum depression,” says Diane Brown-Young, MD, a staff physician in the department of obstetrics and gynecology at the Cleveland Clinic Willoughby Hills Family Health Center in Ohio.
Causes and Risk Factors of Postpartum Depression
Postpartum depression may result from a combination of different factors. Researchers believe that, in general, genetics, hormonal changes, and emotional issues are key contributors.
“After giving birth, hormone concentrations drop by a hundredfold within a matter of days,” says Katherine Wisner, MD, the director of the Asher Center for the Study and Treatment of Depressive Disorders at Northwestern Medicine in Chicago. The sudden plunge may create disturbances in mood, particularly in women who have a prior history of depression or anxiety.
Periods of hormonal fluctuation, such as menstrual cycles or perimenopause, are associated with major depressive episodes, adds Dr. Wisner. The fluctuations that occur during and after pregnancy may affect certain neurotransmitters (chemical messengers in the brain) or brain function in other ways.
“This massive drop in hormones, along with the initiation of breastfeeding, disrupted sleep, and adapting to motherhood, all contribute to the risk of developing depression,” Wisner says.
Risk Factors for Postpartum Depression
- History of depression or bipolar disorder
- Symptoms of depression during or after a previous pregnancy
- Having family member who’s been diagnosed with depression, postpartum depression, or another mood disorder like premenstrual dysphoric disorder
- Having a stressful life event within the past year, such as job loss, death of a loved one, domestic violence, or personal illness
- Medical complications during childbirth, such as premature delivery or having a baby with medical problems
- Having twins, triplets, or other multiple births
- Having conflict or relationship issues with your spouse or partner
- Having an unwanted or unplanned pregnancy
- Having mixed feelings about the pregnancy
- A lack of strong emotional support from others
- Having financial difficulties
- Being younger than 20
- Being a single parent
- Having a baby with medical needs
- Having a baby who cries very often
Men and Postpartum Depression
Sleep Deprivation and Postpartum Depression
How Is Postpartum Depression Diagnosed?
Postpartum depression often goes unaddressed, in part because parents may be ashamed of feeling down during what they believe “should” be a time of joy. But a proactive approach to treating depression is best for everyone concerned.
That’s why it’s so crucial to open up about any feelings you may be experiencing during prenatal visits or during the typical six-week follow-up appointment with your ob-gyn after your baby is born.
Treatment and Medication Options for Postpartum Depression
Regardless of the extent of your symptoms, it’s important to get proper treatment during this important time in your life and the life of your baby. The first step is talking to your healthcare provider.
Talk Therapy for Postpartum Depression
You can seek counseling in your local area or opt for online postpartum depression therapy.
Medication Options for Postpartum Depression
Each mother should make that decision personally, in consultation with their doctor, considering factors like medical history and personal circumstances.
Electroconvulsive Therapy for Postpartum Depression
For women with severe postpartum depression who experience postpartum psychosis — a rare but serious medical condition that can cause hallucinations, delusions, and paranoia — a doctor may recommend electroconvulsive therapy (ECT) if their symptoms aren’t improving with medicine.
Prevention of Postpartum Depression
If you’re planning to become pregnant, or as soon as you do, it’s important to tell your doctor if you have a personal or family history of any mental health conditions, especially previous episodes of postpartum depression. Your doctor can then be sure to check in with you throughout your pregnancy for signs or symptoms of depression.
Lifestyle Changes for Postpartum Depression
- Make healthy lifestyle decisions. Although it’s definitely a challenge to focus on yourself with a new baby, it’s important for mothers who have postpartum depression to take time to do things like eat healthfully, exercise, get enough sleep, and avoid alcohol, which can exacerbate mood swings.
- Practice self-care and rest. Enlist your partner, a friend, or a family member to watch the baby — or hire a sitter — then get out of the house and do something for yourself or take time to rest.
- Set realistic expectations for yourself. Treatment can help, but it may take some time before you feel like yourself again. In the meantime, don’t feel pressured to check off everything on your to-do list.
- Say yes to caregiving help. Take people up on their offers to help. Your partner or friends and family members can help around the house, watch the baby so you can sleep, run errands, and be there to listen when you need to talk.
- Don’t isolate yourself. Talk with your partner, friends, or family members about how you’re feeling. You may want to join a support group with other mothers who’ve experienced postpartum depression and can share experiences and coping skills.
Postpartum Depression Prognosis
Complications of Postpartum Depression
If you notice any of these changes in someone you love or are close to, it’s important to seek help right away, so that both mother and baby remain safe.
Research and Statistics: How Many People Have Postpartum Depression?
Disparities and Inequalities in Postpartum Depression
While postpartum depression can affect anyone of any race, some research suggests that members of Black, Indigenous, and People of Color (BIPOC) communities are especially vulnerable.
Black Americans and Postpartum Depression
Hispanic Americans and Postpartum Depression
American Indian and Alaska Native Women and Postpartum Depression
Postpartum Depression and Related Conditions
- Persistent depressive disorder
- Generalized anxiety disorder
- Postpartum psychosis
- Postpartum post-traumatic stress disorder
- Obsessive-compulsive disorder
The Takeaway
- While complicated emotions, including sadness, can be normal after pregnancy, some women experience more debilitating depressive symptoms, known as postpartum depression.
- Genetics, hormonal changes, emotional issues, and life circumstances can all play a role in causing postpartum depression.
- Symptoms of postpartum depression usually improve with treatment, which can include talk therapy, medications, and lifestyle changes.
Common Questions & Answers
Resources We Trust
- Mayo Clinic: Mayo Clinic Minute: Postpartum Depression Is More Than Baby Blues
- Cleveland Clinic: Postpartum Depression
- The American College of Obstetricians and Gynecologists: Postpartum Depression
- U.S. Department of Health & Human Services Office on Women’s Health: Postpartum Depression
- MedlinePlus: Postpartum Depression
- What Is Postpartum Depression? Cleveland Clinic. April 12, 2022.
- Symptoms of Depression Among Women. Centers for Disease Control and Prevention. May 15, 2024.
- Dagher RK et al. Perinatal Depression: Challenges and Opportunities. Journal of Women's Health. February 2, 2021.
- Postpartum depression: Symptoms & causes. Mayo Clinic. November 24, 2022.
- Wynter K et al. Sleep, mental health and wellbeing among fathers of infants up to one year postpartum: A scoping review. Midwifery. September 2020.
- Pedersen SC et al. “I Wanted to Be There as a Father, but I Couldn’t”: A Qualitative Study of Fathers’ Experiences of Postpartum Depression and Their Help-Seeking Behavior. American Journal of Men's Health. June 11, 2021.
- Wang D et al. Factors Influencing Paternal Postpartum Depression: A Systematic Review and Meta-Analysis. Journal of Affective Disorders. October 1, 2021.
- Niel MS et al. Perinatal depression: A review. Cleveland Clinic Journal of Medicine. May 1, 2020.
- Screening and Diagnosis of Mental Health Conditions During Pregnancy and Postpartum. American College of Obstetricians and Gynecologists. June 2023.
- What Is Perinatal Depression? American Psychiatric Association.
- Earls M et al. Incorporating Recognition and Management of Perinatal Depression Into Pediatric Practice. American Academy of Pediatrics. January 1, 2019.
- Postpartum Depression. U.S. Department of Health and Human Services Office on Women’s Health. October 17, 2023.
- Postpartum Depression. Centers for Disease Control and Prevention. April 5, 2024.
- Carlson K et al. Postpartum Depression. StatPearls. August 12, 2024.
- Antidepressants. Cleveland Clinic. March 1, 2023.
- FDA Approves First Treatment for Postpartum Depression. U.S. Food and Drug Administration. March 19, 2019.
- FDA Approves First Oral Treatment for Postpartum Depression. U.S. Food and Drug Administration. August 4, 2023.
- What Should I Know About Zuranolone and Postpartum Depression? American College of Obstetricians and Gynecologists. February 2024.
- Postpartum depression: Diagnosis & treatment. Mayo Clinic. November 24, 2022.
- Cipolla S et al. Safety of electroconvulsive therapy (ECT) in pregnancy: a systematic review of case reports and case series. Archives of Women's Mental Health. April 1, 2024.
- Perinatal Depression: Preventive Interventions. U.S. Preventive Services Task Force. February 12, 2019.
- Putnick D et al. Trajectories of Maternal Post Partum Depressive Symptoms. Pediatrics. November 1, 2020.
- Rogers A et al. Association Between Maternal Perinatal Depression and Anxiety and Child and Adolescent Development A Meta-Analysis. JAMA Pediatrics. September 14, 2020.
- Postpartum Psychosis. Cleveland Clinic. September 13, 2022.
- Admon LK et al. Trends in Suicidality 1 Year Before and After Birth Among Commercially Insured Childbearing Individuals in the United States, 2006-2017. JAMA psychiatry. February 1, 2021.
- Maternal Mental Health. World Health Organization.
- Birth Data. Centers for Disease Control and Prevention. January 28, 2025.
- Black Maternal Mental Health Issue Brief. Policy Center for Maternal Mental Health. December 8, 2023.
- Burchfield TN et al. Rates of Major Depressive Disorder and Bipolar Disorder in Black and White Postpartum Women. Journal of Clinical Psychiatry. November 20, 2024.
- Waller R et al. Clinician-reported childbirth outcomes, patient-reported childbirth trauma, and risk for postpartum depression. Archives of Women's Mental Health. August 28, 2022.
- Ponting C et al. Postpartum Depressive Symptoms in Low-Income Latinas: Cultural and Contextual Contributors. Cultural diversity & ethnic minority psychology. February 27, 2020.
- Heck J. Postpartum Depression in American Indian/Alaska Native Women A Scoping Review. The American Journal of Maternal/Childhood Nursing. January-February 2021.
- Postpartum Psychiatric Disorders. Massachusetts General Hospital Center for Women’s Mental Health.

Angela D. Harper, MD
Medical Reviewer
Angela D. Harper, MD, is in private practice at Columbia Psychiatric Associates in South Carolina, where she provides evaluations, medication management, and psychotherapy for adults.
A distinguished fellow of the American Psychiatric Association, Dr. Harper has worked as a psychiatrist throughout her career, serving a large number of patients in various settings, including a psychiatric hospital on the inpatient psychiatric and addiction units, a community mental health center, and a 350-bed nursing home and rehab facility. She has provided legal case consultation for a number of attorneys.
Harper graduated magna cum laude from Furman University with a bachelor's degree and cum laude from the University of South Carolina School of Medicine, where she also completed her residency in adult psychiatry. During residency, she won numerous awards, including the Laughlin Fellowship from the American College of Psychiatrists, the Ginsberg Fellowship from the American Association of Directors of Psychiatric Residency Training, and resident of the year and resident medical student teacher of the year. She was also the member-in-training trustee to the American Psychiatric Association board of trustees during her last two years of residency training.
Harper volunteered for a five-year term on her medical school's admission committee, has given numerous presentations, and has taught medical students and residents. She currently supervises a nurse practitioner. She is passionate about volunteering for the state medical board's medical disciplinary commission, on which she has served since 2015.
She and her husband are avid travelers and have been to over 55 countries and territories.

Paula Derrow
Author
Paula Derrow is a writer and editor in New York City who specializes in health, psychology, sexuality, relationships, and the personal essay. She was the articles director at Self magazine for 12 years, and has worked at many other national magazines, including Glamour, Harper’s Bazaar, and American Health. Her writing has been featured in The New York Times Ties column, its Modern Love column, Refinery29, Real Simple, Tablet, Cosmo, Good Housekeeping, Woman’s Day, and more.
Derrow also covers health for New York Presbyterian/Weill-Cornell Hospital in New York City. She has ghost edited a number of health books and health-related memoirs. She is the editor of the Publisher’s Weekly-starred anthology Behind the Bedroom Door: Getting It, Giving It, Loving It, Missing It.
