What Is Ovulation Pain (Mittelschmerz)?

Signs and Symptoms of Ovulation Pain (Mittelschmerz)
- Light vaginal bleeding
- Clear vaginal discharge
- Low back pain
- Nausea
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Causes and Risk Factors of Ovulation Pain (Mittelschmerz)
- Appendicitis
- Ectopic pregnancy
- Endometriosis
- Pelvic inflammatory diseases from STIs, like chlamydia
How Is Ovulation Pain (Mittelschmerz) Diagnosed?
- Blood tests
- Computed tomography (CT) scan
- Pelvic ultrasound
- X-ray
- A swab of cervical fluid to test for an STD
Treatment and Medication Options for Ovulation Pain (Mittelschmerz)
Medication Options
NSAIDs include:
- Aspirin
- Ibuprofen (Advil, Motrin)
- Naproxen (Aleve)
Complementary and Integrative Therapies
Home Remedies
Try the following for heat remedies:
- Heating pads
- Hot baths or showers
Prevention of Ovulation Pain (Mittelschmerz)
Other foods lower inflammation and may reduce pain. These foods may help with pain related to the menstrual cycle:
- Vegetables: Spinach, broccoli, sweet potatoes, Brussels sprouts
- Fruits: Berries, oranges, apples
- Legumes: Beans, peas, lentils
- Whole grains: Brown rice, oatmeal
- Animal proteins, like red meat, chicken, and eggs
- Dairy products
- Refined grains, like white bread and white rice
- Fried foods
How Long Does Ovulation Pain (Mittelschmerz) Last?
Complications of Ovulation Pain (Mittelschmerz)
How Many People Have Ovulation Pain (Mittelschmerz)?
Disparities and Inequities in Ovulation Pain (Mittelschmerz)
Conditions Related to Ovulation Pain (Mittelschmerz)
- Appendicitis Inflammation of the appendix, an organ in the lower belly
- Ectopic pregnancy When a fertilized egg implants and starts to grow outside of the uterus, often in a fallopian tube
- Endometriosis Tissue similar to the lining of the uterus that grows in other parts of the abdomen and causes pain
- Ovarian cyst A fluid-filled sac that forms in the ovary
- Ovarian torsion When an ovary twists around
- Pelvic inflammatory disease (PID) An infection of the reproductive organs
- Scar tissue Scarring from a C-section or other abdominal surgery that causes organs in the belly to stick together (adhesions)
The Takeaway
- Ovulation pain affects around 40 percent of women who are of reproductive age.
- It may be caused by the follicle stretching and then rupturing to release the egg.
- The pain is most often felt in the lower belly on the same side as the follicle.
- Mittelschmerz usually lasts only a few hours and is manageable with over-the-counter pain relievers and a heating pad.
Common Questions & Answers
Resources We Trust
- Cleveland Clinic: Ovulation Calendar: What It Is and How to Use It
- Mayo Clinic: Mittelschmerz
- Physicians Committee for Responsible Medicine: Using Foods Against Menstrual Pain
- NHS: Ovulation Pain
- Planned Parenthood: Can birth control help with period cramps?
- Mittelschmerz. Mayo Clinic. February 13, 2024.
- Brott NR et al. Mittelschmerz. National Library of Medicine. February 13, 2024.
- Ovulation Pain. Cleveland Clinic. February 9, 2023.
- Ovulation Pain. NHS. January 30, 2023.
- Mid-Menstrual Cycle Pain (Mittelschmerz). Harvard Medical School. February 10, 2024.
- Complementary & Alternative Therapies. Royal Women's Hospital.
- Using Food Against Menstrual Pain. Physicians Committee for Responsible Medicine.
- Dysmenorrhea. Cleveland Clinic. May 22, 2023.
- General Approaches to Medical Management of Menstrual Suppression Author: American College of Obstetricians and Gynecologists’ Committee on Clinical Consensus–Gynecology. American College of Obstetricians and Gynecologists. September 2022.

Kara Smythe, MD
Medical Reviewer
Kara Smythe, MD, has been working in sexual and reproductive health for over 10 years. Dr. Smythe is a board-certified fellow of the American College of Obstetricians and Gynecologists, and her interests include improving maternal health, ensuring access to contraception, and promoting sexual health.
She graduated magna cum laude from Florida International University with a bachelor's degree in biology and earned her medical degree from St. George’s University in Grenada. She completed her residency in obstetrics and gynecology at the SUNY Downstate Medical Center in Brooklyn, New York. She worked in Maine for six years, where she had the privilege of caring for an underserved population.
Smythe is also passionate about the ways that public health policies shape individual health outcomes. She has a master’s degree in population health from University College London and recently completed a social science research methods master's degree at Cardiff University. She is currently working on her PhD in medical sociology. Her research examines people's experiences of accessing, using, and discontinuing long-acting reversible contraception.
When she’s not working, Smythe enjoys dancing, photography, and spending time with her family and her cat, Finnegan.
